Loneliness and outsiders Essay Example for Free

Loneliness and outsiders Essay An outsider like crippled Crooks has no one to protect him, all he has is his American Civil Law book which defends his rights as a individual living in the U. S. A and seems to give him a certain comfort knowing that not anyone can argue against his tattered old book. Just as all of his feelings are exposed, Curleys wife threatens him and once again, he withdraws himself back to the liniment which seems to be the only thing in the world that makes Crooks feels better, even if he is ostracised from the rest. Curleys wife is one of the most significant characters to the novel because she shows loneliness on different levels. Because of being married to Curley she has a high status in the ranch, but this is exactly why she has no one but herself. Workers are afraid of getting too close to her in case innocent talking turns into more which could cost them their jobs or even lives. Nevertheless she is led to seek solace with the other men even if they are at the bottom of the social hierarchy on the ranch. And due to all the isolation, the only way to get noticed by the other men is to be a charmer, but this is what makes her so misunderstood. She expresses her true feelings about what could have been to Lennie while he sits on the hay and absorbs absolutely nothing but reflects on the poor little pup that he unintentionally killed. Curleys wife reminisces about how she could have been a Hollywood star and had all the superficial items that so many celebrities buy. Throughout her time on the ranch she has always thought her mother was the reason why Hollywood never became a reality for her, she said, I never got that letter, I always thought my old lady stole it. So I married Curley. This was her dream while on the ranch and like so many others, it shows how much of an outsider and a gullible person she was. In her life there had always been dominant figures like her mother and then Curley. So she has no real idea about how to be autonomous and become more of an independent woman. It could be said that she doesnt know how to interact correctly with people, persistently asking sympathetic rhetorical questions and also being very manipulative and discerning. These virtues are what make Curleys wife such a great character, she has no official name but is possibly one of the most complex characters to depict. Lennie is a simple person, mentally and literally. No one actually understands what he is saying most of the time because the ranch workers have never seen anyone so perplexed and bewildered as he. Without George he would be lost in life, Lennie relies on him to eat and to get him out of trouble whenever its needed most. Even though he blows arguments out of proportion by saying things like, I wouldnt eat no ketchup if it was right here beside me although he really does want the ketchup and is just playing on his own innocence. In one perspective Lennie is quite clever because if there is an opportunity where he can get George to take pity on him, then he will take it, but the majority of the time he is just retarded through no fault of his own. In the book sometimes Lennie is compared to an animal, like when he didnt want to give the mouse to George but then handed it over and started to sulk, Slowly, like a terrier who doesnt want to bring a ball back to its master, Lennie approached. And another time was when he was walking along the dusty road with George, He walked heavily, dragging his feet a little, the way a bear drags his paws. Steinbeck chooses to describe him as an animal to symbolise the title, Of Mice and Men, maybe Lennie is the mouse and George is the man or the other way round. Thats how Lennie is an outsider, because hes an amoral animal who doesnt know his own strength, which is sometimes practical, but when he handles creatures and humans too ruthlessly, he does not know when to stop and that is when the exertion begins for George and Lennie. Lennie and George stick together through thick and thin, even when times get complicated, George seems to find a way out for the pair of them. Circular narrative is when something happens in a story and after a while it occurs again. Throughout the novel Lennie repeats phrases and quotes to George that they have already talked about previously, like the whole ketchup scenario, tending the rabbits, owning and living off the fat of the land etc. This shows that Lennie knows George so well that he assumes all there is to talk about is rabbits and land. That is what makes him a lonesome man because all the conversation is about the same thing and whatever he wants to talk about. All the characters in Of Mice and Men go through a form of loneliness and a feeling of not belonging. At times they can be self-centred which is mainly when two characters are in discussion which each other but not paying attention to the other. Maybe this is one of the reasons that loneliness strikes them, as they do not listen and are all wrapped up in their own impenetrable worlds. But this is what makes the book Of Mice and Men so fascinating to read, all the people have their own problems and dreams because they all share the strong emotions of loneliness and individuality, and even though they may think that they are all diverse, the audience can grasp that each person is more and more like the other.

G Proteins :: Biology Essays Research Papers

G Proteins Proteins play various important roles in inter-neuronal communication. Receptor sites are made up of proteins and the ion channels in the cell membranes are proteins. The link between the receptor sites and the protein channels sometimes is the guanine nucleotide-binding protein, better known as G Protein. (1) The basic structure and function of these shall be explored in the following. In order for neuron communication to occur, the post-synaptic neuron must have receptor sites for the neurotransmitters released by the pre-synaptic neuron. Also, these neurotransmitters, by binding on to the receptors, must bring about a change in the post-synaptic neuron, namely an EPSP (excitatory post-synaptic potential) or an IPSP (inhibitory post-synaptic potential), which may or may not lead to an action potential triggering in the post-synaptic neuron. EPSPs and IPSPs are produced in the post-synaptic neuron due to variations in either the Na+ or Cl- concentrations within the neuron. A change in concentration occurs when the protein channels which gate ion flow, permit Na+ or CL- to migrate across the cell membrane. The question now is, what causes the protein channels to open to Na+ or Cl-. In essence, there are three manners in which the ion flow can come about. The simplest way in which neurotransmitter-receptor binding can cause the opening of the protein channels is when the receptor is located immediately on top of the protein channel. Once a neurotransmitter binds on to the receptor, it causes the protein channel to permit ion flow. Receptors can also be acting on protein channels in more indirect fashion, via a second messenger system. A second messenger system is characterized by a G Protein's inclusion in the transduction of "signals from the transmembrane receptors to intracellular effectors." (1) That means, the binding of a neurotransmitter to a receptor activates a G Protein, which causes the protein channels gating ion flow to open. For this, two general mechanisms exist. Before they can be explained, however, the structure and dynamics of the G Protein must be considered. G Proteins are heterotrimic substances, i.e. they are composed of three subunits, alpha, beta and gamma. The alpha subunit of a G Protein is looked upon as the active subunit, as it binds GDP (guanine diphosphate) when it is inactive, but exchanges GDP for GTP (guanine triphosphat) when active (2) and acts as the "messenger" between the receptor sites and the effector. The beta and gamma subunits aid the alpha subunit to bind to membranes.

Childcare system Essay

Many parents that have kids want to stay at ome during the early years of the children’s youth, but after those years they can’t afford to go back to work. Over 50% of moms that usally stay home and want to go to work but just can’t afford to acording to Ms. Truss. About 17% of moms that did work couldn’t earn enough to be able to have money that would last awhile. â€Å"While 12% cited a lack of job opportunities.† Ms. Truss believes that stuff like this shouldn’t stop people from helping the 52% of mom’s find an affordable childcare so that they can go out and looks for an affordable job. Mrs. Truss wants to have a deregulated childcare system, unlike the other childcares, to have a sinle nursery double with the amount of children they are responsable for. â€Å"Anand Shukla, Chief Executive of the Family, Parenting Insitute, and Daycare Trust wonder if carers and the self-employed will be eligible for this financial support and said something about the devil will be in detail†. The Labour has warned if they cut the nursery staffing levels, it could threaten child safty of the children that are being taken cared of while there parents are working. If stuff like this keeps happening, and they do cut nursery staffing levels, i think the problem would get worse, kids might be killed from carlessness from the lowered class nursery staff, more parents would stay home to protect there kids. If they want to provent stuff like this, they can’t cut the nusery staffing level and have to find something that is less important they can cut to be able to let mothers keep there jobs and so there kids can be safe. They could cut off stuff like entertainment or stuff like amusment parks, just some examples but in my oppion, taking care of the future generation is more important than these two examples. As long as they don’t take drastic messures like cutting nursery staffing levels, the future for them looks pretty good as long as they cut stuff of less important value.

Essay about Chapter One of Dickens Great Expectations

Chapter One of Dickens Great Expectations The title of the novel that I studied is, Great Expectations, written in the 19th century by Charles Dickens. Pip, an orphan often goes to the cemetery to mourn for his dead parents and brothers. While mourning one day, a convict hiding in that same cemetery scares him. All that he thinks of is to listen and obey the man. As the story evolves, we are also introduced to the sentimental part of Pips life. He is in love with a girl named Estella but unfortunately, she doesnt like him. When Pip becomes the perfect gentleman, he inherits some fortune. He mistakes the real provider thinking it is Miss Havisham, until one night he meets the convict again.†¦show more content†¦Also in the first chapter, we see how Pip is very helpless in his state. By saying this, I mean that his sister is always beating him whenever he returns home from the church late at night. What he thinks or does do not matter to his sister and he always ends up keeping his point of view to himself. As a resul t, he suppresses his feelings deep inside him. I find him rather submissive for a boy of his age. When the convict keeps on being harsh to him and scares him, he decides to get him a file, and I would get him what broken bits of food I could, and I would come to him at the Battery, early in the morning, (chapter 1, pg 4,line 10-12). On the other hand, the rude man that we meet in chapter thirty-nine is not that helpless at all. He has a home, a lot of money, as well as a lot of pride. Furthermore, he values people by social standard as he tells Magwitch that I cannot wish to renew that chance intercourse with you of long ago, under these different circumstances, (chapter 39, pg 301, line 35-36). On top of that, he has been educated and can now read regularly so many hours a day (chapter 39, pg 298, line 10-11). He becomes a gentleman in life but he is refusing Magwitch, the man who actually made him great as said in the book not to disguise that I wished him gone (chapter 39, pg 302, line 13-14). It actually happens that he forgetsShow MoreRelatedEssay about Dickens Great Expectations712 Words   |  3 PagesDickens Great Expectations The novel Great Expectations uses the central character, Pip, to depict the ups and downs of a young child on a quest to become not only a man, but a gentleman. Dickens uses a variety of different techniques to create mood, setting, and atmosphere. Charles Dickens grew up in the nineteenth century, when times were hard and punishments were extremely harsh. So harsh you could be imprisoned or even hanged for stealing a loaf of bread. 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